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Description
PGC-1 is the master transcriptional regulator of genes involved in mitochondrial biogenesis and oxidative metabolism and is particularly expressed in skeletal muscle and adipose tissue [83]

McSpadden says

This effect supports weight loss efforts as part of an overall lifestyle approach that includes diet and exercise
[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Hu E.-H., Tsai M.-L., Lin Y., Chou T.-S., Chen T.-H

Am J Med 129:26-29

2003 Nov-Dec;17(6):545-52
