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Through coordinated GLP-1R and GIPR activation, tirzepatide enhances glucose-dependent insulin secretion, improves glycemic control, contributes to lipid homeostasis, and reduces appetite and food intake, supporting its clinical use in obesity and type 2 diabetes [13]

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Yet, because Wegovy, Mounjaro, and Nevolat are not recommended during pregnancy or breastfeeding, treatment should be stopped well before planned conception for those wishing to get pregnancy