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Until then, patient safety must remain the primary consideration

Impact of canagliflozin on kidney and cardiovascular outcomes by type 2 diabetes duration: a pooled analysis of the CANVAS program and CREDENCE trials

Even if the theoretical mechanism has not been confirmed in humans, the potential for stimulating residual disease or recurrence is not worth any benefit

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Administered as a once-weekly subcutaneous injection, tirzepatide is typically initiated at 2.5 mg and increased by 2.5 mg every 4 weeks to a target dose of 5-15 mg as tolerated