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Wegovy contains a higher dose of semaglutide and is specifically FDA-approved for chronic weight in adults who are overweight
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The mean weight loss among participants in its phase 1 trial was 13 percent of their starting body weight after 12 weeks
In terms of proliferation, liraglutide attenuates VSMC proliferation induced by Ang II through eliciting cell cycle arrest and activating AMPK [120]
Together, these studies will further define the cardiometabolic, renal, and rhythm-related benefits of GLP-1 RAs, potentially expanding their use beyond glycemic control
