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doi: 10.1210/endo.139.9.6288

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Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study

Helpful supporting habits can include: Eating slowly and noticing the first signs of fullness Adding protein to each meal to stay full longer Including fiber from vegetables, fruits, and whole grains Drinking water regularly through the day Doing light to moderate movement most days, such as walking Keeping a relatively consistent sleep schedule Many people find that once constant hunger is under control, these simple habits feel much easier to follow

40 Reasons for discrepancies in magnitudes of effect could be that trial participants were generally enrolled with a higher baseline HbA1c, higher level of dysregulation, and longer diabetes duration, which could cause higher absolute differences between baseline achieved HbA1c levels at the end of the trial

There is no universally optimal timing