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Roches oral GLP-1 receptor agonist CT-996obtained in the $2.7 billion acquisition of Carmot Therapeuticsreduced body weight by more than 6% at four weeks versus placebo in a Phase I trial.
The first biosimilar formulation of a GLP-1 receptor agonist, liraglutide, has recently been marketed, at a lower acquisition cost than the original formulation, whilst oral semaglutide remains the only currently available GLP-1 receptor agonist that is administered orally
