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Weight loss and delayed gastric emptying following a south American herbal preparation in overweight patients

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Bergmann NC, Lund A, Gasbjerg LS, Meessen ECE, Andersen MM, Bergmann S, Hartmann B, Holst JJ, Jessen L, Christensen MB, et al

41 Appendage of the amino acid sequences of either cagrilintide or pramlintide to the C-terminus of semaglutide resulted in significantly diminished potency at the AMYR, with a 2050-fold decrease compared to cagrilintide

PMID 23440284

Consider a response ceiling for the current step

However, research suggests that up to 40% of the weight lost while on GLP-1s may come from lean body mass, which includes muscle and bone