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In the context of T2D, weight loss with the GLP-1 RAs reaches a plateau after around 6 months of treatment

Due to its necessity in myelin sheath maintenance, thiamine deficiency may also cause peripheral sensorimotor neuropathy [3]

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Karakasis P., Patoulias D., Fragakis N., Mantzoros C.S

E., Hu, P

A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control

Sodiumglucose co-transporter 2 (SGLT2) inhibitors exert hypoglycaemic effects by inhibiting glucose reabsorption at the proximal convoluted tubules, causing glycosuria, natriuresis and volume contraction (Figure 1).5 Besides SGLT2 inhibition, incretin-based therapies have also been used in recent years for the treatment of T2D ( Figure 2 )