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Description
Morales, D
While most patients tolerate GLP-1 injections well, common side effects like nausea, vomiting, diarrhea, and constipation tend to improve over time

For these cases, Al-Aly wondered if what he was hearing from his patients about how they were able to quit drinking or smoking after starting GLP-1 medication might apply more broadly to any substance
If these mechanisms translate consistently into humans, this could reshape how we think about patient selection and treatment goalsespecially in individuals who may not achieve substantial weight reduction but still derive meaningful hepatic benefit

Bicarbonate gums (like Chooz or some Orbit varieties) are slightly more effective

Given these considerations, the therapeutic approach in older patients with T2D is complex, particularly in those who have functional dependence, frailty, dementia, or who are at end-of-life
