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PlexusDx patients considering breastfeeding should discuss these molecular realities with their prescriber, as this evidence helps contextualize risk differently than outdated assumptions about all medications

doi: 10.3109/03639045.2010.526123

common brand names include Ozempic and Wegovy (semaglutide), Mounjaro and Zepbound (tirzepatide, a dual GIP/GLP-1 drug), Trulicity (dulaglutide), Victoza and Saxenda (liraglutide), Byetta and Bydureon (exenatide), Adlyxin (lixisenatide), and Rybelsus (oral semaglutide), with generic options currently including liraglutide and exenatide in some markets

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GLP-1 RAs provide sustained central and peripheral GLP-1R activation that blunts appetite via hypothalamusvagusNTS circuits, improves metabolic health, and may reduce alcohol and other substance-related craving and reward signals

Baker WL, Smyth LR, Riche DM, Bourret EM, Chamberlin KW, White WB