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Description
GLP-1 RAs, including semaglutide, liraglutide and dual GIP/GLP-1 RAs, such as tirzepatide, are used in the treatment of diabetes mellitus and weight loss
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compounding regulations
The following table lays the two ligand classes side by side
In clinical trials of once-daily or BID GLP-1 receptor agonists (liraglutide, lixisenatide, or exenatide BID), mean changes in body weight were 2.1 to 2.9 kg for monotherapy and +0.3 to 3.6 kg in combination with oral antihyperglycemic therapies (13,14,18)
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