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Cell 167:843857.e814 Ethics declarations Funding This work was supported in part by Deutsches Zentrum fr Diabetesforschung (DZD), Alexander von Humboldt Foundation, Helmholtz Alliance ICEMED through the Initiative and Networking Fund of the Helmholtz Association, and the Helmholtz cross-program topic Metabolic Dysfunction

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Figuring out who will pay for this is the challenge

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Meaning, if the drug lasts a month (or 3-4 months) and you react badly, itll take time for your body to clear it

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Edmonds D

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Every expert agrees that the most common side effects of GLP-1s are constipation

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In the STEP-1 trial, 1,961 patients were followed for 68 weeks and underwent randomization to semaglutide or placebo plus lifestyle intervention resulting in14.9% weight loss in the semaglutide group versus 2.5% in the placebo group [33]

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