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There is no single GLP-1 medication with universally fewer side effectstolerability varies significantly between individuals based on genetics, metabolic markers, and dosing approach
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So the slower the fat loss, these the you know, assumption is or the conclusion is that it's more sparing of your muscle

10.1007/s10753-019-01164-1 [DOI] [PubMed] [Google Scholar] 32.Nie N, Bai C, Song S, Zhang Y, Wang B, Li Z

The study found that while both medications produced substantial health benefits and were similarly safe and well tolerated, tirzepatide resulted in greater weight loss and a larger reduction in waist circumference than semaglutide

Interestingly, the STEP-8 study 22 revealed a higher incidence of psychiatric events with liraglutide 3 mg (15.0%) compared to semaglutide 2.4 mg (5.6%) and placebo (10.6%)
