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What is the evidence regarding the safety of new obesity pharmacotherapies

The additive sympathomimetic effects increase risk of arrhythmias, palpitations, and hypertensive episodes, particularly in individuals with pre-existing heart conditions or borderline blood pressure

Insurance coverage decisions typically require demonstration of obesity through BMI thresholds with or without metabolic comorbidities but do not specifically require established cardiovascular disease

Clin Exp Otorhinolaryngol 18(4):296305 [DOI] [PMC free article] [PubMed] [Google Scholar] 7.Jiang W, Li W, Cheng J, Li W, Cheng F (2023) Efficacy and safety of liraglutide in patients with type 2 diabetes mellitus and severe obstructive sleep apnea
