glp 1 drug side effects Part 2 of a 3-Part Series; GLP-1 Medications for Weight Loss The GLP-1 Agonists and Obesity:

Lastly, the systemic effects of GLP-1RAs, such as body weight loss [103] and potential reduction in muscle mass [104], pose significant challenges for elderly individuals with neurodegenerative diseases

He J, Kang Y, Lian C, Wu J, Zhou H, Ye X

The bottom line GLP-1 drugs are not a replacement for insulin, and they are not officially approved for T1D (outside of the new 2026 ADA recommendation for T1D with obesity)

doi: 10.1016/j.japh.2023.10.037 [DOI] [PubMed] [Google Scholar] 162.Langeskov EK, Kristensen K

Pooled analysis including these two studies in addition to SELECT and FLOW [31] reported that semaglutide reduced the risk of hospitalization or urgent visits due to heart failure by 41% (HR 0.59, 95% CI 0.410.82) in HFpEF patients compared with placebo [32]

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