glp-1- GLP-1 Weight Loss Options * Bariatric Fusion’s bariatric multivitamins and supportive supplements are formulated by a team of bariatric practitioners to support nutrient absorption for those who have undergone ASMBS Understanding GLP-1 and Its Role

Blood Sugar Effects Both medications improve glucose metabolism: Liraglutide: HbA1c reduction of 0.5-1.0% at weight loss doses Originally developed for diabetes (Victoza) Modest glucose benefits at Saxenda doses Semaglutide: HbA1c reduction of 1.0-1.8% at diabetes doses Greater glucose improvement than liraglutide Significant benefit for prediabetes and diabetes For patients with diabetes or prediabetes, semaglutide provides greater metabolic benefit

Four out of 23 patients on GLP-1 RAs manifested bezoars, compared with 0 out of 77 of the patients who were not on GLP-1 RAs

Common side effects of GLP-1s are gastrointestinal issues, including nausea, vomiting, diarrhea, dehydration, and constipation

JAMA 314, 687699 (2015)

Downregulation of GLP-1 and GIP receptor expression by hyperglycemia possible contribution to impaired incretin effects in diabetes

GLP-1 receptor agonists are a class of drugs used in popular medications such as Novo Nordisk's Ozempic, which contains the active ingredient semaglutide and is approved to treat Type 2 diabetes