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9 All-cause mortality reduction In a systematic review and meta-analysis of cardiovascular outcome trials (ELIXA, LEADER, SUSTAIN-6, EXSCEL, Harmony Outcomes, REWIND, PIONEER 6), use of GLP-1RAs reduced all-cause mortality by 12% compared with placebo (hazard ratio [HR] 0.88

Plecanatide: a new guanylate cyclase agonist for the treatment of chronic idiopathic constipation

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The latest formulationsthe Wegovy pill and orforglipron (Foundayo)have shown comparable results to injectables in recent clinical trials