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Cannon CP, Pratley R, Dagogo-Jack S, Mancuso J, Huyck S, Masiukiewicz U, Charbonnel B, Frederich R, Gallo S, Cosentino F, Shih WJ, Gantz I, Terra SG, Cherney DZI, McGuire DK

Most telehealth GLP-1 programs require a BMI of 27 or higher with a weight-related health condition, or a BMI of 30 or higher without comorbidities, consistent with FDA labeling for chronic weight management
Glucagon receptor agonism to facilitate weight loss Glucagon is a peptide secreted from alpha cells within the pancreas
The studies are event driven and powered to proof non-inferiority

However, in terms of immune system effects, there is limited evidence indicating that DPP4 inhibition impairs immune function

While pancreatic enzymes (lipase, amylase) are not routinely monitored, they might be checked if pancreatitis is suspected based on symptoms
