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This receptor profile allows researchers to examine how simultaneous activation of incretin- and glucagon-related pathways affects intracellular signaling, hormone pathway coordination, and broader metabolic system responses

10.1038/s41598-024-56818-4 Sci Rep

FDA-approved GLP-1 receptor agonists include exenatide, liraglutide, dulaglutide, semaglutide, and lixisenatide

However, the effects of GLP-1 on dopamine phenotypes are inconclusive, as a previous study showed Exn-4 administration decreased dopaminergic signaling through increased dopamine transporter (DAT) in rats but not in humans [154]