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In short, the results of the association between adiponectin and bone metabolism are quite discrepant between preclinical and clinical studies

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doi: 10.1358/dot.2014.50.10.2214156

These adjustments typically resolve within days as your body stabilizes
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Dietary supplements are not a substitute for prescription medication or professional care, and they do not replace evaluation or treatment for menopause, including decisions about hormone therapy
