va semaglutide criteria for use Veterans' experience with VA weight loss medications? Subcutaneous weekly semaglutide with automated

While nausea, vomiting, and diarrhea are the most commonly reported gastrointestinal adverse effects with GLP-1-based therapies (occurring in 15-40% of patients depending on the agent and dose), FDA prescribing information for several of these medications does list dyspepsia (indigestion) and, in some cases, gastroesophageal reflux disease (GERD) as reported adverse reactions

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Gonadal steroids, particularly estrogen, reduce food intake by potentially enhancing the sensitivity of the female brain to other anorexigenic factors such as leptin (4)

While there are varying perspectives on this issue, in a viewpoint that I was pleased to co-author with Sam Klein and Kevin Hall just published in JAMA, we suggest that the concern regarding physical frailty or sarcopenia with GLP-1-based medications may not be as grounded as some argue

People taking Eli Lillys obesity drug, Zepbound, lost nearly 50% more weight than those using rival Novo Nordisks Wegovy in the first head-to-head study of the blockbuster medications

Approval for type 2 diabetes and obesity In the process of treating type 2 diabetes, the injectable medications were found to also result in weight loss