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The most common side effects of tirzepatide are: Nausea (especially when first starting) Vomiting Diarrhea Constipation Indigestion Stomach pain Dehydration Headaches Dizziness Fatigure It also causes appetite losswhich is the pointbut can sometimes become too extreme, making it difficult to maintain adequate caloric intake

Phase 1 involves small-scale studies, typically 20100 people, primarily in healthy volunteers, to determine safety, tolerability, and appropriate dosing

This is well characterized ( Tolhurst et al., 2012 )

Recent research, notably the pivotal SELECT trial, has confirmed their suitability for non-diabetic subjects with obesity and established CVD

"Our program is designed to address these pitfalls

Developed by Eli Lilly