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GLP-1GIPlanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPAR, PPAR and PPAR, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse models via synergistic incretin and PPAR activity.

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7.7% 27

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Polycystic ovary syndrome affects hormonal balance and weight regulation in up to 20% of women

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