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Heres what it feels like your appetite quiets, you fill up more quickly and you dont have that incessant snack voice eking away in your head all day

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Laboratory studies have also shown that GLP-1 receptor activation can reduce reward-seeking behaviors in models exposed to drugs or highly palatable foods, supporting the biological plausibility of these observations (2 Trusted Source The glucagon-like peptide-1 analogue exendin-4 decreases the rewarding value of food and drug rewards

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Consequently, individuals in a state of decreased basal dopamine signaling, known as a hypodopaminergic state, may possess a greater risk for post-GLP-1RA treatment-associated psychiatric conditions such as depression and suicide, where polymorphisms in the DRD2 receptor are likely implicated in this pathophysiology [160,161]