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The main mechanisms by which GLP1RAs promote tumor apoptosis encompass the cAMPPKAdependent pathway, the BMP4/Smad signaling pathway, the PI3K/Akt/mTOR signaling pathway, and the NF-B signaling pathway

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The importance of such a proximal-to-distal GIP-GLP-1 axis for human physiology is, however, questionable

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