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The samples were acquired at 25 C according to literature procedure using a Biacore X100 instrument equipped with a CM5 sensor chip (GE Healthcare Biosciences) 48

The beneficial effects of lipid-lowering agents on the efficacy of incretin-based drugs need to be demonstrated in humans before conclusions can be drawn regarding the validity of this approach in type 2 diabetes, especially since the ability of GLP-1 agonists to stimulate beta cell proliferation, well documented in rodents [13], has yet to be shown in humans

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