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Moreover, GLP-1 RAs slow gastric emptying, thereby blunting postprandial glucose and lipid excursions, though diminished tolerance to this effect may develop during prolonged administration of extended-release preparations

Patient-level studies: A 2025 American Journal of Managed Care analysis of 9,848 GLP-1 prescriptions (20182022, Colorado Health system) found an overall fill rate of 60.1% ( [30] )

References Meier JJ