how long can you be on glp 1 should take GLP-1 drugs? Study links longer use to lower heart risk Curious about what happens after
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doi: 10.1056/NEJMoa2302392 [DOI] [PubMed] [Google Scholar] 200.Newsome PN, Buchholtz K, Cusi K, et al
GLP-1 analogues delay gastric emptying ( When initiating GLP-1based therapy, clinicians should adhere to the principle of do no harm , particularly during the early phases of treatment when gastrointestinal adverse effects are most likely to emerge ( Potentially the easiest way to prevent nausea and vomiting is by starting at a low dose ( In most cases of Grade 1 or 2 nausea, maintaining the current dose for one to two additional dosing intervals is sufficient to allow symptom resolution
The N-terminal region of GLP-1 is considered critical for receptor activation, whereas the C-terminal region predominantly facilitates receptor binding
It seems to depend on the purpose for which people take GLP-1s
But the possibility of safely reducing long-term steroid exposure is a significant potential benefit of tirzepatide for this population
Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pedersen SD, et al
