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SGLT2is have shown reliable benefits in reducing cardiovascular mortality

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Endogenous GLP-1 released from the gut acts directly on vagal afferents, which relay information from the abdomen to the brain and regulate multiple physiological systems

The phase 2b SYMMETRY trial, a multicenter, randomized, double-blind, placebo-controlled study, included 181 patients with compensated cirrhosis (Child-Pugh A) due to MASH (78% with histological diagnosis and 22% with cryptogenic cirrhosis attributed to MASH) assigned to receive efruxifermin at doses of 28 or 50 mg, or placebo (1:1:1), for 96 weeks

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Clients on GLP-1s tend to have increased shedding and overall thinning, especially around the crown and hairline, says colorist and stylist Temur Hamilton, who owns Manhattan salon TEMUR