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However, as noted above, intervention trials of oral SCFA butyrate supplementation have shown no effect on glycaemic control or other markers of diabetes regulation in either type 1 or type 2 diabetes [116, 122, 123, 206], probably because the site of delivery does not mimic endogenous production

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Mark Gilbert, a nutritionist at PortionIQ, a science-led range of GLP-1 friendly shakes, bites, soups and drinks, says people are at risk of dehydration when calories are substantially restricted