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Approximately 42% of online pharmacies offering semaglutide operate illegally, which poses significant risks such as receiving counterfeit products or substandard drugs

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35 , 36 Despite the high risk of nonadherence, patients with prediabetes and in GLP1 RA treatment were not associated with an increased risk of addon glucoselowering treatment, which could be indicative of an effective weight reduction and control of the HbA1c simply weight reduction, or adverse effects

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Patients who can sustain treatment long-term achieve cumulative benefits that justify the investment