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Zhang H, Sturchler E, Zhu J, et al

Beneficial Effects of Yebra mate in Obesity

however, agents such as insulin or sulfonylureas increase hypoglycemia risk compared to placebo (48) and when used concomitantly with GLP-1 receptor agonists (1318)

277: R1144-1151

Activation there reduces food intake, and it is this central action, as much as any peripheral effect, that drives the weight loss seen with GLP-1 drugs
