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Clinical-stage obesity-related drugs targeting GLP-1R, GIPR, or GDF-8 through November 2024. Quality, Off-the-Shelf, Metabolic Pathway Proteins from KACTUS The targets involved in obesity treatment encompass various pathways that contribute to the onset and progression of the condition

Ph 2 datathat showed weight loss of between 9.4% and 14.7% after 36 weeks on the drug compared to 2.3% for the placebo group and is currently in Ph 3

Based on: Lebrun LJ, Lenaerts K, Kiers D, Pais de Barros JP, Le Guern N, Plesnik J, et al

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In a survey, employers told the Business Group on Health that they arent yet seeing evidence of long-term health benefits from taking GLP-1s for weight loss, leaving them unsure how to manage costs while continuing to cover them.