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Clinics in Bend, Oregon & Seattle, Washington Also serving California, Oregon, & Washington via virtual visits How GLP-1 Therapy Works at Flow Wellness Flow Wellness offers multiple GLP-1 options tailored to your goals and preferences

PMID: 17352367

some studies suggest that pro-inflammatory cytokines IL-1 and TNF- suppress the expression of CYP7A1 and NTCP, leading to decreased BA synthesis and a reduction in the hepatic-enterohepatic circulation rate, thereby contributing to BA metabolic disorders

However, as is often the case for many new medicines, there could be limitations in translating pre-clinical effects to the patient population

Safety Considerations and Who Should Discuss GLP-1 with a Healthcare Provider GLP-1 agonists carry known risks: gastrointestinal side effects, pancreatitis risk in susceptible individuals, and thyroid concerns in some populations

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