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A better understanding is urgently needed to address the root cause of obesity stigma, which manifests in our misperceptions of obesity.16 This understanding must lead to definitive actions that provide equality to the treatment of obesity within a chronic disease framework, one in which PwO will not be discriminated against and will be equally supported

There is direct evidence comparing semaglutide to sitagliptin and dulaglutide in patients inadequately controlled on one oral antidiabetic drug (OAD), and to exenatide or insulin glargine in patients with inadequate glycemic control with one or two OADs, however data are lacking for other comparators