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By 3 months, those on exenatide had a mean reduction of 7.7 monthly headache days (from a baseline of ~ 22 days/month) compared to a 1.5 day change in the placebo arm, although the between-group difference did not reach statistical significance (exenatide: p = 0.069 within-group

Some patients may experience nausea, digestive discomfort, decreased appetite, or mild gastrointestinal symptoms

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While sulfur burps are not specifically listed as a distinct adverse effect in formal clinical trial data, they represent a plausible manifestation of the medication's known impact on gastric emptying and digestive function
