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GLP-1 RA therapy significantly improved both exercise capacity and HRQoL in individuals with obesity-related HFpEF regardless of diabetes status, but had no effect on these parameters in in HFrEF patients

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Non-Alcoholic Fatty Liver Disease (NAFLD): its effects on weight loss and metabolic regulation may also benefit individuals with non-alcoholic fatty liver disease (NAFLD), a condition often associated with obesity and type 2 diabetes

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Recent FDA approvals have expanded the indication for semaglutide to include the reduction of major adverse cardiovascular events (MACE), such as heart attack, stroke, and cardiovascular death, in adults with established cardiovascular disease and obesity