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Thus, substitution of (replacing rather than adding) an agent with cardiorenal benefit might be appropriate if people are at or near A1c target

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35 Impact of GLP1-RAs on diabetes and inflammation Exendin administration in diabetic mice has been shown to attenuate inflammatory responses by upregulating regulatory T cells

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Importantly the inferred sequence of the platypus GLP-1 peptide (pGLP-1) differs in 11 of the 30 amino acids (37%) compared to human GLP-1 (hGLP-1, Fig

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