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Description
Independently of these peripheral actions, GLP-1RAs show direct cerebral effects in animal stroke models, such as reduction of infarct volume, apoptosis, oxidative stress, neuroinflammation, excitotoxicity, bloodbrain barrier permeability, and increased neurogenesis, neuroplasticity, angiogenesis, and brain perfusion

The medication, sold under the name Mounjaro, will be available in six different doses and come in an auto-injector pen.
Adverse psychiatric effects associated with GLP-1 RAs, including depression, anxiety, and suicidal ideation, are noted in pharmacovigilance analyses, with variations among different GLP-1 RAs

Provider oversight and coaching included
The program is designed to expand access to a high-demand class of medications that have been financially out of reach for many.

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