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In the same 2025 study by Qeadan and colleagues, individuals with a history of opioid use disorder (n=503,747) prescribed GLP-1 medications had about a 40% lower rate of opioid overdose events during the 2-year follow-up period (Qeadan et al., 2025)

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Key Considerations Before Starting Treatment Its worth noting that, like any weight loss approach, GLP-1 medication is not a quick fix

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Journal of Affective Disorders, 180, 104-111

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