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retatrutide ly3437943 glp-1 gip glucagon LY3437943, a novel triple glucagon, GIP, and receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept Retatrutide Guide 2023: Weight Loss,
Description
Table 1: Retatrutide Binding Affinity (Ki values) Table 2: Retatrutide Functional Potency (EC50 values) The binding kinetics reveal that retatrutide exhibits highest affinity for the glucose-dependent insulinotropic polypeptide receptor, with a human Ki value of 0.057 nM, representing exceptional binding strength [6] [7] [8]

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