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Brain Health: Alzheimers disease risk dropped by 12%, and the likelihood of developing dementia decreased by 8%

It is also worth considering that fatigue attributed to GLP-1 therapy may actually reflect underlying conditions such as hypothyroidism, anemia, sleep apnea, or depression, which should be evaluated if tiredness persists

Patients treated with GLP-1RA will need to self-inject agents or have them administered subcutaneously anywhere from twice daily to once weekly depending on formulation

Dulaglutide is an option when eGFR is above 15 mL/min/1.73 m, but adjustments may be necessary for severe impairment

Studies of mice lacking the sulfonylurea receptor-1 (SUR1) and pore-forming Kir6.2 subunits of K ATP channels provide additional evidence for a K ATP channel-dependent action of GLP-1 to stimulate insulin secretion