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and it reduces glucagon release, thereby lowering hepatic glucose production

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For retatrutide , phase 2 data published in the New England Journal of Medicine (2023) demonstrated substantial mean weight reductions over 48 weeks in adults with obesity among the highest figures reported for any pharmacological agent to date

As a triple receptor agonist, Retatrutide may influence gastrointestinal function by delaying gastric emptying and modifying gut motility patterns