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Discontinued treatment, low maintenance dosage led to reduced effectiveness of GLP-1 medications on body weight and blood sugar levels

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Manufacturers of medications used for diabetes and weight loss failed to warn doctors and patients about severe gastric side effects.

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Methods We conducted a systematic review of studies from PubMed, Embase, and Cochrane databases (until November 2024), as well as relevant abstracts from Digestive Disease Week (DDW) 2024 and American College of Gastroenterology (ACG) 2024 to assess the impact of GLP-1 receptor agonists (GLP-1 RAs) on EGD