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Major clinical trials, including the STEP-1 extension and SURMOUNT-4, provide valuable insights into this process

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GLP-1 medications alone have robust safety data across thousands of patients

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This research brief focuses on the GLP-1 receptor agonists semaglutide and tirzepatide that are branded under multiple product names, and which were originally developed for managing type 2 diabetes

According to the Summaries of Product Characteristics (SmPCs), nausea is very common with most GLP-1 medications, while abdominal distension, eructation (belching), and flatulence are typically classified as common side effects, though frequencies differ between products