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Comparison with Non-GLP-1 Users When compared to matched patients taking only metformin, GLP-1 users showed higher rates of several deficiencies at 12 months, particularly: Vitamin D deficiency B vitamin deficiencies Thiamine deficiency Other interesting notes from the study 92% of patients hadn't seen a dietitian in the 6 months before starting GLP-1s The average time to first dietitian visit was 128 days (over 4 months) The authors note that GLP-1s can reduce energy intake by up to 39%, and also stress the importance of hydration monitoring (GLP-1s may suppress thirst)

1 It makes sense once you understand how these drugs actually work

However, individuals sensitive to caffeine or other stimulants should approach with caution, as it might lead to jitters or insomnia

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