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A subsequent combined analysis of the STEP 14 studies showed that gastrointestinal adverse events (nausea, vomiting, diarrhea, and constipation) were more common with SMG than with placebo but typically mild to moderate and transient, with weight loss being largely independent of gastrointestinal adverse events [103]
Erbil D, Eren CY, Demirel C, Kker MU, Solarolu I, Eser HY (2019) GLP-1s role in neuroprotection: a systematic review
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