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Evidence-based management if lacking because of paucity of clinical data given the rarity of cardiac angiosarcomas

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Wadden, T.A., Bailey, T.S., Billings, L.K., Davies, M., Frias, J.P., Koroleva, A., Lingvay, I., ONeil, P.M., Rubino, D.M., Skovgaard, D., Wallenstein, S.O.R., Garvey, W.T

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Several mechanisms may be involved in this potential association, some of which include sudden weight loss and hyperactivity of the hypothalamic-pituitary-adrenal axis

The MAC trial, a randomised crossover study from Loma Linda University, enrolled 35 overweight and obese adults with abdominal obesity and at least one additional cardiometabolic risk factor