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These findings are interesting, but they are not proof that GLP-1s prevent dementia

Quick Answer: Prednisolone and Wegovy can be taken together as there is no absolute contraindication, but their opposing metabolic effects on weight and blood glucose require careful monitoring and individualised clinical assessment

The prominent reason for this observation is likely the formation of larger and more stable oligomers for the lipidated analogues compared with the nonlipidated GLP-1-Am, which is discussed in the following section

Supply and Distribution Constraints This sudden increased demand for GLP-1s eventually led to supply shortages starting in March 2022, with a key contributing factor being the underlying difficulty of manufacturing peptide-based drugs