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Literature Search Strategy A structured literature search was performed across PubMed/MEDLINE, Embase, Scopus, Web of Science, and the Cochrane Library to identify relevant publications addressing body composition changes during GLP-1 receptor agonist therapy, the effects of testosterone and TRT on lean mass and skeletal muscle, and the intersection between metabolic weight loss and androgen physiology

DIPEA (16 ml) was added to the reaction mixture at 25-30C and stirred for 2 hr at the same temperature

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